Is agriculture doing enough to control antibiotic resistance?

April 1, 2016, 6:45 a.m. ·

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Cattle are sometimes treated with antibiotics toward the later stages of feeding when their grain-heavy diet can cause illness. (Photo by Grant Gerlock, NET News/Harvest Public Media)

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Some of the most important medicines doctors prescribe to fight infections are losing effectiveness. Bacteria are building resistance to our antibiotics and the White House is calling on doctors - and farmers - to help protect public health.


Antibiotics are part of many livestock feeding operations. They’re often used to treat sick animals. But some farmers also put antibiotics in feed or water to keep animals from getting sick or make them gain weight faster. One problem is, not all those drugs stay on the farm.

Environmental engineer, Xu Li, at the University of Nebraska-Lincoln measures antibiotic resistance in farm fields where livestock manure is spread as fertilizer.

“Not all the antibiotics will be absorbed by the animal,” Li said. “So a certain part of it will be released into the environment.”

The bacteria not killed by the medicines develop resistance to the drugs. Li’s research shows those resistant bacteria can build up.

University of Nebraska-Lincoln environmental engineer, Xu Li, says researchers are looking at using anaerobic digesters and other technologies to reduce the level of antibiotic resistant bacteria in livestock manure. (Photo courtesy UNL)

“Recently people also (found) if an environment receives livestock manure from facilities that have been using antibiotics, then the level of antibiotics and antibiotic resistant genes in the soil environment will increase,” Li said.

Over time the level of resistant bacteria can return to its natural level. But increases in environmental resistance could pose a risk for public health. Not all bacteria are a direct risk to people, but the concern is that resistance could potentially spread to pathogens that are a threat.

Last year, the White House released a national plan to get a handle on antibiotic resistance and created the Presidential Advisory Council on Combatting Antibiotic-Resistant Bacteria to follow its progress. This week, those experts gathered in Washington, D.C. to give an update on how the plan is working at hospitals and on the farm.

Mike Apley, a member of the presidential council and an instructor in veterinary medicine at Kansas State University, told the council antibiotic resistance is not a new issue for farmers.

“Judicious use guidelines have been initiated by producers and veterinary groups in association with federal agencies for quite some time,” Apley said.

But federal agencies are changing some of the rules for how antibiotics are used on farms in an effort to cut down their use. The FDA is asking pharmaceutical companies to stop allowing antibiotics to be used just to make animals grow faster. The agency also set a new veterinary feed directive, or VFD. It means, in many cases, antibiotics that were sold over-the-counter now must be prescribed by a vet.

Apley says the new rules are raising questions in the livestock industry about when antibiotics are really necessary.

“So the VFD has been a real instigator of having those conversation about when should we, how should we (give antibiotics),” Apley said.

David Wallinga, a physician and public health advocate with the Natural Resources Defense Council, believes the best way to reduce antibiotic use in humans and livestock is to set specific targets. (Photo courtesy NRDC)

But some public health advocates are calling on the council and federal agencies to do more to enforce changes in antibiotic use, particularly on the farm.

David Wallinga, a physician and public health advocate with the Natural Resources Defense Council, says the FDA should set benchmarks to reduce antibiotic use for operations like cattle feedlots, hog barns, and poultry farms.

“(It) turns out they have set targets on the humans side,” Wallinga said. “They’ve said that we want to reduce the antibiotics in clinics by 50 percent and we want to reduce the antibiotics in hospitals by 20 percent.”

The FDA has not set targets for agriculture, he says, even though most of the antibiotics important for human health are used to treat animals, not people. Even now, under new guidelines, many drugs can still be fed to healthy animals to keep them from getting sick.

“So it’s really unclear to us that if you just get rid of the growth promotion on the label that you’re really going to change the way people use these antibiotics,” Wallinga said.

Even if the FDA did set targets for agriculture to use fewer antibiotics, it would be hard to tell if it was working. There is no system collecting data on how farmers use antibiotics. And the presidential council says that is a problem.

“I think there is quite a bit of recognition that without baseline data it’s going to be very difficult to monitor our progress,” said Elizabeth Jungman of the Pew Charitable Trusts who led the council’s working group on surveillance. “That said, the growth promotion changes happen this year. The veterinarian feed directive happens this year. The surveillance systems weren’t funded.”

The council is asking Congress to provide funding to the FDA and Department of Agriculture to create monitoring programs. Until then it will be hard to know exactly what changes are happening on the farm, and what it might mean for our health.


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